Florence Single Family Properties for Sale

Our website features the best real estate search for single family properties available in Florence and surrounding areas. It is the only site you will ever need! It is easy-to-use and updated by the official REALTOR®’s database every 15 minutes.

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Newest Florence Single Family Homes for Sale

310 W Sumter, Florence $240,950 ▼

New Home! Move in Ready! One Level Living at its BEST! Contemporary Style where Modern embraces Southern Comfort! 3 BRMS/2 Baths, 2 car garage w/ electric car hookup! Pri...

3 Beds
2 Baths
20244579 MLS

7417 E National Cemetery Road, Florence image

7417 E National Cemetery Road, Florence $319,500

Majestic Comfort Meets Modern Design. Step into this beautifully crafted 3-bedroom home featuring a split floor plan designed for privacy and functionality. The Owner’s ...

3 Beds
2 Baths
20244436 MLS

2527 S Cashua, Florence $2,200 ▲

Great commercial office space available on Cashua in the Shoppes at Celebration. Tenant to pay base rent, insurance, CAM and pro rata share taxes (428 a month subject to...

2 Baths
20244212 MLS

620 W Evans Street - Suite A, Florence image

620 W Evans Street - Suite A, Florence $2,200

Open concept executive office space for lease offering exceptional visibility as you enter Downtown Florence. As you step inside 620 W Evans - Suite A, you’ll be greeted ...

1 Baths
20244157 MLS

2295 Hoffmeyer Road - Building 2, Florence image

2295 Hoffmeyer Road - Building 2, Florence $22,725

Unlock a unique opportunity with this impressive +/- 36,360 sqft warehouse for lease located in the new and thriving West End District of Florence, SC. Perfectly situated...

2 Baths
20244147 MLS

420 W Cheves St, Florence $1,400 ▼

Looking for the perfect office space in a central location? This approximately 1,500 sq ft downstairs office space at 420 C W Cheves St. is available for rent and offers ...

1 Baths
20243792 MLS

313 S Gaillard St, Florence $165,000

Three bedroom oand one bathroom home in Florence, SC is seconds from McLeod Hospital. With over 1,000 sq ft this property in such a central location this property is perf...

3 Beds
1 Baths
20242516 MLS

620 W Evans Street, Florence $4,500

Outstanding office building available for lease located at 620 W Evans Street near Downtown Florence, South Carolina. 620 W Evans is a standalone building with private pa...

2 Baths
20240788 MLS

130 Mustang Rd, Florence $449,900

2 Brick Ranch Homes---1) Home 3/1 Super Nice inside & 1 - Brick Ranch Home 3/2 coming available soon 1 -14x60 Singlewide Mastercraft All OF THIS ...

3 Beds
1 Baths
20232816 MLS

185 N Dargan, Florence $4,800

Large commercial spaces in downtown Florence for rent. Property has newer windows, newer roof, and a nice newer back door! According to owner property on 1st floor has 44...

2 Baths
126045 MLS

Provided courtesy of The Coastal Carolinas Association of REALTORS®. Information Deemed Reliable but Not Guaranteed. Copyright 2026 of the Coastal Carolinas Association of REALTORS® MLS. All rights reserved. Information is provided exclusively for consumers’ personal, non-commercial use, that it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.